1334 Eckles Ave, Food Science & Nutrition Building
St. Paul, MN 55108
United States
Middle East Technical University, Ankara, Turkey · B.Sc. in Biology | September 2014-June 2019 · Minor in Food Science | September 2017-June 2019 - Middle East Technical University, Ankara, Turkey · M.Sc. in Biotechnology | January 2020-August 2022 · Thesis: Phage Therapy Against Contamination of Pathogenic Escherichia coli Strains (O104:H4, O157:H7, and O26) During Garden Cress (Lepidium sativum Linn.) Vegetation
Biography
Irem Iskender is a Ph.D. candidate in Food Science at the University of Minnesota–Twin Cities, where she conducts research on bacteriophages and cell-free gene expression systems. Her doctoral work focuses on developing and optimizing in vitro platforms for bacteriophage synthesis, biomanufacturing, and functional analysis, with applications in food safety and pathogen control.
Irem earned her M.Sc. in Biotechnology from Middle East Technical University, where she investigated phage therapy against pathogenic Escherichia coli in agricultural systems. She also holds a B.Sc. in Biology with a minor in Food Science. Her interdisciplinary background bridges microbiology, biotechnology, and food safety.
As a Graduate Research Assistant, Irem contributes to an NSF-funded project on cell-free engineering and biomanufacturing of bacteriophages. Her research integrates molecular biology, transposon sequencing, and computational analysis to study phage–host interactions and improve phage production platforms. She has co-authored peer-reviewed publications and regularly presents her work at national and international conferences.
In addition to her research, Irem is actively involved in teaching and outreach as a Teaching Assistant for biomanufacturing workshops and undergraduate courses. She is a member of several professional societies, including ASM and IAFP, and has received multiple awards for her research and presentations.
Areas of Interest
- Bacteriophage biology and engineering
- Cell-free gene expression systems (CFE/TXTL)
- Phage biomanufacturing and rebooting
- Phage–host interactions
- Foodborne pathogen control
- Transposon sequencing (Tn-seq)
- Synthetic biology
Select Publications
- McFarlane, J.A., Hansen, E.G., Cortes-Ortega, E., Iskender, I., Noireaux, V., & Bowden, S.D. (2023). A ToxIN homolog from Salmonella enterica serotype Enteritidis impairs bacteriophage infection. Journal of Applied Microbiology, 134(12), lxad299.
- Cortes-Ortega, E., Hansen, E.G., Iskender, I., Farmer, M.L., Martinez-Villalobos, J.M., Vitt, J.D., & Bowden, S.D. (2024). Isolation and characterization of Salmonella enterica- and Escherichia coli-specific bacteriophages of the genus Epseptimavirus from wastewater in Minnesota. Archives of Virology, 169, 255.
- Iskender, I., & Soyer, Y. (2023). Phage therapy against pathogenic Escherichia coli (O104:H4, O157:H7, and O26) strains in irrigation water during garden cress (Lepidium sativum Linn.) vegetation. Foodborne Pathogens and Disease, 20(12), 553–562.