Daniel D. Gallaher
Daniel Gallaher received his graduate training at the University of California, Davis. After completing his doctoral degree, he joined the faculty in 1983 at North Dakota State University. In 1988 he joined the Department of Food Science and Nutrition at the University of Minnesota, where he is now a professor. His research interests include dietary influences on colon cancer, particularly the effects of pre- and probiotics, whole grains, cruciferous and apiaceous vegetables, and dietary fat, as well as the effect of dietary fiber on cholesterol metabolism, diabetes, body composition, and satiety. He is a member of the University of Minnesota Cancer Center, the Minnesota Obesity Center, and the Healthy Foods, Healthy Lives Institute. He has served on the editorial board for the Journal of Nutrition and is a reviewer for many journals. He has also served as Director of Graduate Studies in Nutrition at the University of Minnesota. He is a member of the American Society for Nutrition and the Obesity Society. He received the College of Human Ecology McFarland Creative Teaching Award in 1998, the Outstanding Teacher of the Year for 2002-2003 by the College of Agriculture, Food, and Environmental Sciences Student Board, the College of Agriculture, Food and Environmental Sciences Distinguished Teaching Award (Tenured category) in 2006. He served as Associate Dean for undergraduate programs in the College of Human Ecology from 2001 to 2006.
Areas of Interest
- Biochemical and Physiological Nutrition
- Cancer Research
- Diabetes and obesity
NUTR 5622 - Vitamin and Mineral Biochemistry
FSCN 4613 - Experimental Nutrition
Our research program focuses overall on the influence of dietary components on the development of chronic diseases, with emphasis on events occurring within the gastrointestinal tract. Currently we are examining the effect of several different dietary components on an animal model of colon cancer. Specifically, we have recently found that cruciferous vegetables have a profound effect on reducing the number of precancerous lesions in carcinogen-treated rats. We have also examined the effect of different types of wheat on colon cancer risk, and demonstrated that red wheat is far more effective at reducing precancerous lesions in carcinogen-treated rats than white wheat. We are also currently studying the effects of different types of whole grains on the development of type II diabetes, using an animal model of this condition. We have also conducted several studies that demonstrate that dietary fibers that have a high viscosity within the gastrointestinal tract reduce body fat, without necessarily reducing body weight. That is, the viscous dietary fibers cause a shift in body composition. Studies are ongoing to understand the mechanism of this effect.
Islam, A. and Gallaher, D.D. Wheat type (class) influences development and regression of colon cancer risk markers in rats. Nutr. Cancer. In press.
Jae Kyeom Kim; Daniel D. Gallaher; Chi Chen; Dan Yao; Sabrina P. Trudo. Apiaceous vegetable consumption decreases PhIP-induced DNA adducts and increases methylated PhIP metabolites in the urine metabolome in rats. Journal of Nutrition. 2015;145:442-451.
Mary I Buescher; Daniel D Gallaher; Wheat color (class), not refining, influences colon cancer risk in rats; Nutr Cancer. 2014;66:849-856.
Vamsidhar Yerramsetty; Daniel D Gallaher; Baraem Ismail; Malonylglucoside conjugates of isoflavones are much less bioavailable compared to unconjugated beta-glucosidic forms in rats.; J Nutr. 2014;144(5):631-637.
David A Brockman; Xiaoli Chen; Daniel D Gallaher; High-viscosity dietary fibers reduce adiposity and decrease hepatic steatosis in rats fed a high-fat diet; J Nutr. 2014;144(9):1-8.
Vamsidhar Yerramsetty; Daniel D. Gallaher; Baraem Ismail; Malonylglucoside conjugates of isoflavones are much less bioavailable compared with unconjugated β-glucosidic forms in rats; Journal of Nutrition. 2014;144(5):631-637.
Mary I. Buescher; Daniel D. Gallaher; Wheat color (Class), not refining, influences colon cancer risk in rats; Nutrition and Cancer. 2014;66(5):849-856
David A. Brockman; Xiaoli Chen; Daniel D. Gallaher; High-viscosity dietary fibers reduce adiposity and decrease hepatic steatosis in rats fed a high-fat diet; Journal of Nutrition. 2014;144(9):1415-1422.
U.S. Sorge; T. Molitor; J. Linn; D. Gallaher; S.W. Wells; Cow-level association between serum 25-hydroxyvitamin D concentration and Mycobacterium avium subspecies paratuberculosis antibody seropositivity: A pilot study; Journal of Dairy Science. 2013;96(2):1030-1037.
Natalia Schroeder; Len F. Marquart; Daniel D. Gallaher; The role of viscosity and fermentability of dietary fibers on satiety- and adiposity-related hormones in rats; Nutrients. 2013;5(6):2093-2113.
Daniel D. Gallaher; Sabrina P. Trudo; Nutrition and Colon Cancer; Nutrition in the Prevention and Treatment of Disease. 2013:697-715.
David A. Brockman; Xiaoli Chen; Daniel D Gallaher; Consumption of a high b-glucan barley flour improves glucose control and fatty liver and increases muscle acylcarnitines in the Zucker diabetic fatty rat; European Journal of Nutrition. 2013;52(7):1743-1753.
Moonyeon Youn; A. Saari Csallany; Daniel D. Gallaher; Whole grain consumption has a modest effect on the development of diabetes in the Goto-Kakisaki rat; British Journal of Nutrition. 2012;107(2):192-201.
Ajmila Islam; Anthony E. Civitarese; Robert L. Hesslink; Daniel D. Gallaher; Viscous dietary fiber reduces adiposity and plasma leptin and increases muscle expression of fat oxidation genes in rats; Obesity. 2012;20(2):349-355.
Cynthia M. Gallaher; Daniel D. Gallaher; Sabrina Peterson; Development and validation of a spectrophotometric method for quantification of total glucosinolates in cruciferous vegetables; Journal of Agricultural and Food Chemistry. 2012;60(6):1358-1362.
Barbara Vogel; Daniel D. Gallaher; Mirko Bunzel; Influence of cross-linked arabinoxylans on the postprandial blood glucose response in rats; Journal of Agricultural and Food Chemistry. 2012;60(15):3847-3852.
Julie Triolet; Ahmad Ali Shaik; Daniel D. Gallaher; Michael G. Osullivan; Chengguo Xing; Reduction in colon cancer risk by consumption of kava or kava fractions in carcinogen-treated rats; Nutrition and Cancer. 2012;64(6):838-846.
David A. Brockman; Xiaoli Chen; Daniel D. Gallaher; Hydroxypropyl methylcellulose, a viscous solublefiber, reduces insulin resistance and decreases fattyliver in Zucker Diabetic Fatty rats; Nutrition & Metabolism. 2012:100.
M. Song; S.K. Baidoo; G.C. Shurson; M.H. Whitney; L.J. Johnston; D.D. Gallaher; Dietary effects of distillers dried grains with solubles on performance and milk composition of lactating sows; Journal of Animal Science. 2010;88(10):3313-3319.
Susan B. Fredstrom; Jose Jessurun; Daniel D. Gallaher; Pancreatitis induced in rats by repetitive administration of l-arginine; Pancreas. 2009;38(3):344-345.
Cynthia M. Gallaher; Daniel D. Gallaher; Dried plums (prunes) reduce atherosclerosis lesion area in apolipoprotein E-deficient mice; British Journal of Nutrition. 2009;101(2):233-239.
Natalia Schroeder; Daniel D. Gallaher; Elizabeth A. Arndt; Len Marquart; Influence of whole grain barley, whole grain wheat, and refined rice-based foods on short-term satiety and energy intake; Appetite. 2009;53(3):363-369.
Andrea Y. Arikawa; Daniel D. Gallaher; Cruciferous vegetables reduce morphological markers of colon cancer risk in dimethylhydrazine-treated rats; Journal of Nutrition. 2008;138(3):526-532.
J.A. Renteria-Flores; L.J. Johnston; G.C. Shurson; D.D. Gallaher; Effect of soluble and insoluble fiber on energy digestibility, nitrogen retention, and fiber digestibility of diets fed to gestating sows; Journal of Animal Science. 2008;86(10):2568-2575.
Andrea Y.A. Plate; Daniel D. Gallaher; Effects of indole-3-carbinol and phenethyl isothiocyanate on colon carcinogenesis induced by azoxymethane in rats; Carcinogenesis. 2006;27(2):287-292.
Hyejung Cho; Daniel D. Gallaher; A. Saari Csallany; Conjugated linoleic acid, cis-9,trans-11, is a substrate for pulmonary 15-lipoxygenase-1 in rat; Journal of Agricultural and Food Chemistry. 2005;53(18):7262-7266.
Andrea Y. A. Plate; Daune L. Crankshaw; Daniel D. Gallaher; The effect of anesthesia by diethyl ether or isoflurane on activity of cytochrome P450 2E1 and P450 reductases in rat liver; Anesthesia and Analgesia. 2005;101(4):1063-1064.
A.Y.A. Plate; D.D. Gallaher; The potential health benefits of corn components and products; Cereal Foods World. 2005;50(6):305-314.
Yuqing Yang; Daniel D. Gallaher; Effect of dried plums on colon cancer risk factors in rats; Nutrition and Cancer. 2005;53(1):117-125.
Volker Mai; Hormuzd A. Katki; Hermie Harmsen; Daniel Gallaher; Arthur Schatzkin; David J. Baer; Beverly Clevidence; Effects of a Controlled Diet and Black Tea Drinking on the Fecal Microflora Composition and the Fecal Bile Acid Profile of Human Volunteers in a Double-Blinded Randomized Feeding Study; Journal of Nutrition. 2004;134(2):473-478.
Jinmo Khil; Daniel D. Gallaher; Beef tallow increases apoptosis and decreases aberrant crypt foci formation relative to soybean oil in rat colon; Nutrition and Cancer. 2004;50(1):55-62.
David R. Jacobs Jr.; Daniel D. Gallaher; Whole grain intake and cardiovascular disease: A review; Current Atherosclerosis Reports. 2004;6(6):415-423.
Timothy P. Carr; Kimberly J. Wood; Craig A. Hassel; Rajan Bahl; Daniel D. Gallaher; Raising intestinal contents viscosity leads to greater excretion of neutral steroids but not bile acids in hamsters and rats; Nutrition Research. 2003;23(1):91-102.
H. Cho; D.D. Gallaher; A. Saari Csallany; Nonradiometric HPLC measurement of 13(S)-hydroxyoctadecadienoic acid from rat tissues; Analytical Biochemistry. 2003;318(1):47-51.
Daniel D. Gallaher; Chitosan, cholesterol lowering, and caloric loss; Agro Food Industry Hi-Tech. 2003;14(5):32-35.
Timothy P Carr; Roxana M Cornelison; Blake J Illston; Cindy L Stuefer-Powell; Daniel D Gallaher; Plant sterols alter bile acid metabolism and reduce cholesterol absorption in hamsters fed a beef-based diet; Nutrition Research. 2002;22(6):745-754.
Daniel D. Gallaher; Cynthia M. Gallaher; Gregory J. Mahrt; Timothy P. Carr; Carolyn H. Hollingshead; Robert Hesslink Jr.; John Wise; A glucomannan and chitosan fiber supplement decreases plasma cholesterol and increases cholesterol excretion in overweight normocholesterolemic humans; Journal of the American College of Nutrition. 2002;21(5):428-433.
Russell L. Cowles; Ji-Young Lee; Daniel D. Gallaher; Cindy L. Stuefer-Powell; Timothy P. Carr; Dietary stearic acid alters gallbladder bile acid composition in hamsters fed cereal-based diets; Journal of Nutrition. 2002;132(10):3119-3122.
Christine N. Polkinghorne; Judith M. Olson; Daniel G. Gallaher; Peter W. Sorensen; Larval sea lamprey release two unique bile acids to the water at a rate sufficient to produce detectable riverine pheromone plumes; Fish Physiology and Biochemistry. 2001;24(1):15-30.
A.S. Csallany; S.-S. Kim; D.D. Gallaher; Erratum: Response of urinary lipophilic aldehydes and related carbonyl compounds to factors that stimulate lipid peroxidation in vivo (Lipids (2000) 35 (855-862)); Lipids. 2001;36(1):107.
G.K. Harris; A. Gupta; R.G. Nines; L.A. Kresty; S.G. Habib; W.L. Frankel; K. LaPerle; D.D. Gallaher; S.J. Schwartz; G.D. Stoner; Effects of lyophilized black raspberries on azoxymethane-induced colon cancer and 8-hydroxy-2′-deoxyguanosine levels in the fischer 344 rat; Nutrition and Cancer. 2001;40(2):125-133.
Cynthia M. Gallaher; Jessa Munion; Robert Hesslink Jr.; John Wise; Daniel D. Gallaher; Cholesterol reduction by glucomannan and chitosan is mediated by changes in cholesterol absorption and bile acid and fat excretion in rats; Journal of Nutrition. 2000;130(11):2753-2759.
A.S. Csallany; S.-S. Kim; D.D. Gallaher; Response of urinary lipophilic aldehydes and related carbonyl compounds to factors that stimulate lipid peroxidation in vivo; Lipids. 2000;35(8):855-862.
Linda J. Brady; Daniel D. Gallaher; Frank F. Busta; The role of probiotic cultures in the prevention of colon cancer; Journal of Nutrition. 2000;130(2 SUPPL.):410S-414S.
Jennifer L. Causey; Joellen M. Feirtag; Daniel D. Gallaher; Bryan C. Tungland; Joanne L. Slavin; Effects of dietary inulin on serum lipids, blood glucose and the gastrointestinal environment in hypercholesterolemic men; Nutrition Research. 2000;20(2):191-201.
S.-S. Kim; D.D. Gallaher; A.S. Csallany; Vitamin E and probucol reduce urinary lipophilic aldehydes and renal enlargement in streptozotocin-induced diabetic rats; Lipids. 2000;35(11):1225-1237.
S S Kim; D D Gallaher; A S Csallany; The antioxidants vitamin E and probucol reduce renal enlargement and in vivo lipid peroxidation in streptozotocin-treated diabetic rats.; Lipids. 2000;35:1225-1237.
2015 Advising and Mentoring Award - Graduate and Professional Student Assembly of the University of Minnesota
2006 College of Agriculture, Food, and Envronmental Sciences Distinguished Teaching Award (Tenured Category)
2002-2003 Outstanding Teaching of the Year by the College of Agriculture, Food, and Environmental Sciences Student Board.
2000 Paper selected for the Annual Bibliography of Significant Advances in Dietary Supplement Research 2000, published by the Office of Dietary Supplements of the National Institutes of Health [Gallaher, C.M., Munion, J., Hesslink, R., Jr., Wise, J., and Gallaher, D.D. (2000) Cholesterol reduction by glucomannan and chitosan is mediated by changes in cholesterol absorption and bile acid and fat excretion in rats. J. Nutr. 130: 2753-2759.] The top twenty-five original research papers (out of >450 submitted for consideration) were selected for this bibliography.
1998 College of Human Ecology McFarland Creative Teaching Award